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Serum concentrations of modafinil can be lessened to a clinically important extent in the existence of medicines that induce CYP3A4. These involve rifampin, phenytoin, St John Wort, and efavirenz.In advance of having modafinil, explain to your doctor or pharmacist If you're allergic to it; or to armodafinil; or For those who have any other allergie